Synthesis of functionalized thiophenes and oligothiophenes by selective and iterative cross-coupling reactions using indium organometallics.

Martínez, M. M.; Peña-López, M.; Pérez Sestelo, J.; Sarandeses, L. A.


Org. Biomol. Chem. 2012, 10, 3892–3898 (DOI: 10.1039/c2ob25123j).

trigger text
hidden content

The synthesis of unsymmetrical 2,5-disubstituted thiophenes by selective and sequential palladiumcatalyzed cross-coupling reactions of indium organometallics with 2,5-dibromothiophene is reported. Following an iterative coupling sequence, a-oligothiophenes were synthesized in good yields and with high atom economy.