Synthesis of bench-stable solid triorganoindium reagents and reactivity in palladium-catalyzed cross-coupling reactions

Gil-Negrete, J. M.; Pérez Sestelo, J.; Sarandeses, L. A.

Abstract

Chem. Commun. 2018, 54, 1453–1456 (DOI: 10.1039/c7cc09344f).

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Highlighted in: Knochel, P.; Ketels, M. Synfacts 2018, 14, 414 (DOI: 10.1055/s-0037-1609133).

Bench-stable solid triorganoindium compounds have been prepared by coordination with 4-(dimethylamino)pyridine (DMAP). The solid R3In(DMAP) complexes are obtained from the corresponding solution of R3In in quantitative yield and can be stored for up to several weeks. These reagents show excellent reactivity in palladium-catalyzed cross-coupling reactions with organic electrophiles.