Microwave-assisted direct synthesis of BODIPY dyes and derivatives

Ana Da Lama, José Pérez Sestelo, Luis A. Sarandeses and M. Montserrat Martínez


Org. Biomol. Chem., 2022, 20, 9132–9137 DOI: https://doi.org/10.1039/d2ob01349e

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A microwave-assisted one-pot synthesis of BODIPY dyes from pyrroles and acyl chlorides is reported. This protocol features short reaction times, low temperatures, minimum amount of solvent, scalability, versatility, and good yields of the products. These simple, efficient and sustainable conditions can be also
applied to the synthesis of derivatives such as BOPHY, BOAHY and BOPAHY.