The research group Synthetic and Catalytic Methodologies works at the Research Center for Advanced Scientific Research (CICA) within the group of Molecular Chemistry and Materials. The research is focused on the development methodologies for the synthesis of organic compounds of interest, bioactive compounds or new organic materials. The synthetic tools are mainly related to Organometallic Chemistry and with the use of transition metals in organic synthesis. Since 1997, this research group has developed different projects associated with the synthesis of bioactive natural products, sustainable chemical processes and new reactions of formation of carbon-carbon and carbon-heteroatom bonds. Of particular relevance are the investigations on organometallic indium in reactions catalyzed by transition metals.



Recent publications

Stereospecific indium(III)-catalysed tandem cycloisomerization of functionalized 1,6-enynes: scope and mechanistic insights

Raquel Pérez-Guevara, Luis A. Sarandeses, Rosana Álvarez, M. Montserrat Martínez  and José Pérez Sestelo

Adv. Synth. Cat. 2024,

Indium organometallics in transition metal-catalyzed cross-coupling reactions

M. Montserrat Martínez, Jose Perez Sestelo, and Luis A. Sarandeses

Advances in Organometallic Chemistry 2023, vol 80, pp  177-253 (10.1016/bs.adomc.2023.02.001)

Synthesis of 1H-Isochromenes and 1,2-Dihydroisoquinolines by Indium(III)-Catalyzed Cycloisomerization of ortho-(Alkynyl)benzyl Derivatives

Fabio Seoane-Carabel, Lorena Alonso-Marañón, Luis A. Sarandeses, José Pérez Sestelo

Synthesis 2023, 55,  1714-1723 (10.1055/s-0042-1751383)