The research group Synthetic and Catalytic Methodologies works at the Research Center for Advanced Scientific Research (CICA) within the group of Molecular Chemistry and Materials. The research is focused on the development methodologies for the synthesis of organic compounds of interest, bioactive compounds or new organic materials. The synthetic tools are mainly related to Organometallic Chemistry and with the use of transition metals in organic synthesis. Since 1997, this research group has developed different projects associated with the synthesis of bioactive natural products, sustainable chemical processes and new reactions of formation of carbon-carbon and carbon-heteroatom bonds. Of particular relevance are the investigations on organometallic indium in reactions catalyzed by transition metals.




Ramón, congratulations for the excellent article just published in JOC. A really beautiful piece of work !!!

Recent publications

Indium(III)-catalyzed stereoselective synthesis of tricyclic frameworks by cascade cycloisomerization reactions of aryl 1,5-enynes

Ramón E. Millán, Jaime Rodríguez, Luis A. Sarandeses, Enrique Gómez-Bengoa, and José Pérez Sestelo

J. Org. Chem. 2021, 86, 10.1021/acs.joc.1c00825

Advances in Cross-Coupling Reactions

José Pérez Sestelo and Luis A. Sarandeses

Molecules 2020, 25, 4500; doi:10.3390/molecules25194500

Transition-Metal-Free Oxidative Cross-Coupling of Triorganoindium Reagents with Tetrahydroisoquinolines

Gil-Negrete, J. M.; Pérez Sestelo, J.; Sarandeses, L. A.

J. Org. Chem. 2019, 84, 9778-9785. DOI: